The Espion multifocal ERG system software and hardware has been
developed by Diagnosys LLC to provide an easy to use clinical system
for combined spatial and temporal information on retinal function.
The default 61 and 103 elements (max 243 elements) are available
with both short and long M-sequences.The full M-sequence test takes
8 minutes to perform with variable configurable segments lengths.
Espion Multifocal System Detailed Specifications
Stimulus Features
Both eyes can be tested simultaneously
Ultra-wide field stimulus (90 degrees)
Variable size, scale and type of stimulus:
Hexagonal/dartboard/square stimulus patterns
Extendable stimulus period using filler frames
Variable size, location and color of fixation cross
Variable M-sequence length tailored to hex count
Testing can be stopped periodically to rest the patient
Hardware Features
5 Channel headbox with industry-first 32-bit amplifiers
32" LCD wide angle monitor custom-designed to minimize
luminance artifact and electrical noise
Brightness 1000 cd/m2, Contrast ratio 1000:1
Integrated Power Supply Isolation Unit
3 system configurations:
Stand-alone, cart-mounted with power lift table (shown right)
Stand-alone, bench-mounted (overleaf)
or integrated into the Espion System
Headbox Features
5 isolated channels can be acquired simultaneously (32 bit ADC)
Low pass and high pass filtering
Digital filtering when processing signal
Software Features
Full integration with Espion software
Easy setup of multifocal protocols
Print preview and customizable print layout templates
Export data
Run-time features
Real time trace display during testing
50Hz/60Hz mains removal option
Noise level monitoring
Adjustable real-time blink rejection–rejected blink data is
re-recorded, not simply replaced by "best-guess" data
Smart data averaging
Patient fixation monitoring through built in camera application
Protocol fixation parameters can be adjusted before test run
Analysis Features
Display results as trace array, 2D/3D surface plot and
latency plot
Show all plot types simultaneously
Show left eye, right eye or both simultaneously
View, scale and average traces + restore to
original trace values
Display trace array with amplitude density or latency values
Plot results vs. normals, raw recorded data or combinations
Show viewing angles on all scaled 2D plots
View, scale, change color-code and rotate surface plot
Colorplot for latency, amplitude, amplitude density,
surface variation and normal variation
View response timings in color-coded plot
Hotspot view and modify marker position for implicit times and
amplitudes
Standard manual analysis (single response, group response)
Group analysis of traces (default or customized groups)
Scaling with normalized density or density
View raw data for a test
Database Features
Username and password security option
Different user authorization levels
Industry standard SQL relational database
Client/Server facility to link across the net or through a local network
Automatically generated and time-stamped audit trail
Automatic database backup option
Built-in password security with support for CFR 21 part 11
Normative database available
Optional Infra-red Camera
Infrared fixation camera tracks fixation and automatically
interrupts testing when fixation deviates by a pre-determined
(user-selectable) angle. Camera tracks both eyes and can
measure pupil size so screen luminance can be specified in
Trolands. Eye image displayed in real time on tester's screen.
Desktop Option
The Diagnosys Profile multifocal ERG/Pattern system is
also available in a desktop mounted version.
Espion Profile VEP and PERG
Optional VEP and PERG round out the Espion Profile multifocal
system to create an ideal instrument for neuro-ophthalmology
applications. The large, bright screen coupled with the 32-bit
acquisition system produces VEP and PERG responses of
unprecedented clarity. The screen has been highly engineered
to minimize the luminance artifact that makes most LCD screens
unsuitable for use as VEP stimulators.
Stimulator Features
Calibrated luminance and color
Max resolution of 1366 x 768
75 Hz Frame Rate
6 bit Color/luminance control
Luminance > 1000 cd/m2
Checkerboards, bars, gratings as standard with single
pixel resolution
Multiple operator modes, for different levels of access
Built in password security with support for CFR 21 part 11
Data Acquisition
The data acquisition system is based around a fast DSP microprocessor that
controls and synchronizes data acquisition and stimulator timing independently
from the PC. The system is comprised of 5 differential DC coupled amplifiers
(prevent AC amplifier lockup) with the following specification:
Industry-first 32 bit resolution (<1nV LSB)
Fully isolated
Input range +/- 2.5V max; +/-625 mV default
Automated internal calibration
Integral anti-alias filter
Differential channel input gain matching better than 0.01%
Ultra low noise <1uV RMS
Input impedance greater than 109 ohms
CMRR greater than 110dB at 50/60Hz
4kHz internal sample frequency
Automatic impedance monitor measures each input including ground,
not just each channel
All filtering is performed digitally
Control Computer Option
Touchscreen panel PC, Rugged Laptop, Laptop, or Desktop PC configured to
current highest hardware standard available at time of purchase
USB optical mouse and keyboard included
Power Isolation
The Espion Profile System incorporates transformers required to isolate ancillary
equipment such as a monitor or printer so they will meet medical leakage current
standards. No cumbersome external transformers are needed
Unique lead testing system uses illuminated receptacles to guide lead insertion and indicate electrode contact quality.